I went to a HYPM in the northeast and my best friend in college was from Hawaii (Punahou). Academically, she had no issues, so Punahou obviously prepared her well, as @skieurope noted.
She had a significant amount of culture shock coming to the NE from Hawaii, which had a huge impact on her college years.
It may be something to strongly consider as you consider BS. My friend often expressed some regret that she did not choose a college on the West Coast, which would have allowed her to go home for shorter vacations like Thanksgiving.
She also felt that the West Coast would have been more of a middle ground culturally and weather- wise between Hawaii and the northeast.