Do you think I would die if I take AP Physics, Calc AB, Government, and Human Geography? Or should I do AP Biology instead of Physics?
There is no way to say from the information that you have posted here. Some students do fine with 4 APs, some find it to be too much. Usually Juniors and Seniors can handle this better than younger students, but it depends. Personally I would find physics much easier than biology, but that is me (and apparently NOT most people).
Also, some students do very well at good universities (not Ivy’s) even without having taken any AP classes at all in high school.
Yes, did you not know? Human Geography and Calc AB crest a lethal poison when mixed that will kill someone in just 24 hours 
Seriously though, noone can tell unless you give more information
These guys are right, it depends on you! My experience: physics was dang hard, calculus it depends on your teacher, government is super easy, human geo is super easy, biology was easier than physics. Physics was hard because it is fast paced and lots of math, although taking it with calculus might help since a lot of the math ties in.
Make sure you take Bio, Chem and Physics in HS and ideally an AP version of at least one of those.
What do you want to major in?
If Engineering/Chem, take Physics or Chem.
If pre-med/Bio/Bio Chem, take AP Bio or AP Chem.
If a humanities, then what ever you would like.
Those 4 classes do not seem super crazy hard.
I’m an incoming sophomore, and I am fairly good at math. AP Govt, Human Geo, and Calc I can’t interchange, but I’m wondering if it’s worth it to take an AP Science next year, on top of all that. I’m shooting for valedictorian, and a lot of people are taking three APs next year. Will a fourth weigh down all of my other grades, or will it aid my in my quest to be the best???
Like everyone says, no one knows how well you can handle that many APs. Try not to put too much weight on Val either, and just try your best. Take classes because they are interesting, will aid in graduation req.s, or you need them to save money.
People aiming for Val usually don’t shy away from work/a challenge imo… It’s your decision.
What classes are you taking alongside these?
Assuming AP Physics1 and seeing your prowess in math I don’t see a problem with it. (If physics C, it’s crazy and should be taken alongside calc BC, next year, NOT this year).
Have you take AP’s before?
Keep in mind that this little competition with other high school students doesn’t matter to colleges. The titles of valedictorian and salutatorian come from the times students didn’t go on to college. This distinction thus marked their academic achievements at the end of their education. Nowadays, what matters more is college. As far as highly colleges go, being top 10% is what they want - and colleges don’t like “AP junkies” - they want to see a total of 6-8 AP’s, after which the law of diminishing returns applies. Those AP’s should primarily come from core subjects (calculus, foreign language, English language & composition, one from the three main sciences, History) plus subjects related to your interests.
It’s more important you took each of bio, Chem, and Physics, than if you took only two of these and one extra AP.
All in all, piling up AP’s isn’t the way to go. As Stanford famously put it “it’s not a game of who has the most AP’s, wins”.
Take a balanced schedule that leaves enough time for 8-9 hours of sleep and plenty of time to develop interesting EC’s. Read How to be a high school superstar, by Cal Newport.