College major and high school classes?

So I know for some colleges, let’s say you want to do pre med or something, so colleges might want to see that you have taken AP Bio or something to show that you are somewhat interested in the field. Does an AP score or SAT Subject score “replace” AP Bio as an equally effective way of demonstrating interest?
So for example I took these tests and did well, does that show to colleges that I am actively learning what interests me most?

I am asking this because I might be interested in pre med, but I will have a schedule conflict so I will be unable to take it.

Not all schools like mine offer AP Bio. Colleges will understand. A good AP score will be a good substitute for the class.