Do you any idea of a general direction for college studies, if not a specific major? If your interests lie in the sciences/STEM areas, 101 would be best. If you’re just looking to check off a science to get it out of the way and never have to look at it again, 100 would be a good choice.
If it’s a toss-up, I’d suggest 101 as a more rigorous and valuable choice, with more future options.