That was just the TL;DR 
If you forward just past 1h19m in episode #224 of The Drive, they answer that question specifically. They advocate for 150g of protein a day once over 60. Don Layman, then states that we can only mobilize between 25-60g of protein towards muscle at one sitting. What happens with the single meal approach, especially as we age, is that we can lose weight, but much of it is from loss of lean muscle mass. We lose muscle mass as we age, no matter what we do. We certainly don’t want to accelerate that.
This is all just me parroting Don Layman, a well respected protein biochemist, and Peter Attia.