@Midwest67 - My GYN had me in for blood work five weeks after my hysterectomy, which as we guessed, showed I had very little estrogen (women do still produce some estrogen after menopause, which is why some women are prescribed estrogen-blocking medications such as Tamoxifen after being treated for certain kinds of cancer), so he started me on a prescription cream from a compounding pharmacy that I rubbed into my forearm twice a day; we doubled the dosage once, when I got no relief. With the increased dose, I still got no relief, so we moved to a gel (forgive me if I’ve gotten this backwards, but I know I started with either cream or gel, then switched to the other one). So I switched to the gel and we went through the same thing again; he did more blood work and told me I was no where near the therapeutic level, so for some reason, my body does not absorb the stuff well through the skin. Then he put me on the Minivelle patch, at .01mg/day. He used an analogy of my ‘reservoir being dried up for a long time’ (eight months) and that we were starting high to refill it. I’m telling you, within 3-4 days of starting that patch, the hot flashes started going away, and I was SO relieved - I slept better than I had in more than six months. But within a 3-4 months, I started having some really low-grade PMS symptoms (low-grade headaches and very tender breasts), so when I saw him the next time in six months (and yes, my blood work showed high levels of estrogen) , he lowered me to the .075 mg./day. When I had more blood work in six months, I was not surprised to hear that I was still on the high side as I was still having the occasional PMS symptoms, so he lowered my dose to .05 mg./day and that’s where I’ve been at since last December. When I saw him last week, I knew that my estrogen was going to be low as I’d started to have some very occasional hot flashes and occasional waking up in the middle of the night/throwing off sheets and blankets. But it’s very tolerable, unlike right after my hysterectomy. If it doesn’t get any worse, I can live with this. But yea, my estrogen has really reduced since December so we had a talk about it. I told him I was perfectly fine with it as it is right now, and if the hot flashes and sleep start to get effected again, he said he has some women alternate different prescriptions of patches. With the Minivelle patch, you change it every 3.5 days; I change mine on Wednesday nights and Sunday mornings… one of those days I’d put on a .075 patch, and on the other day I’d put on a .05 patch.
The other part of the equation is what you’re doing already, taking progesterone. When I was having the heavy bleeding and refusing to have the endometrial ablation, he had put me on bio-identical progesterone then, so I was already on it when I had my hysterectomy. The most important thing to remember is that most of those women who were in the 2003 study that showed an increase in cancer while on HRT, they were only on estrogen - they were not taking progesterone. And yes, there can be a correlation between unopposed estrogen therapy and cancer. So anyone on estrogen should be on, and be monitored for their progesterone, too.
One of the reasons we had a more in-depth talk about it last week is that, since I saw him last in December, I had a pretty serious breast cancer scare. My mammogram classification correlated with a 79% chance of malignancy, so I was scared out of my mind for a couple of weeks until I had the biopsy and got the results showing what they saw was just scar tissue. But for a couple of weeks, I was assuming I was going to have surgery, and probably radiation and possibly chemotherapy. One of my biggest worries was my HRT was going to be taken away from me (which he assured me he would not do after I told him what had happened in April with the scare) and I’d go back to a miserable life that I had right after my hysterectomy when I was so sleep-deprived. Even my breast surgeon told me some of his patients are on HRT after a cancer diagnosis because really, for some women, it becomes a quality of life issue. Many doctors these days will suggest certain anti-depressants for hot flashes, but I wasn’t willing to go that route; I preferred the BHRT route and so far, I’m happy with the results, even if it has taken some time to get to a stable/manageable level.