How much time and effort do you put into your CS, Engineering, Science, and Math studies?

To be fair, there were some courses in which for certain sections of exams, I scored the highest in the class.
And I know some friends in which in an average exam score of a 30 (with an A being 32), scored a 100.
It really depends on your goals.
For me, grades were largely unimportant. I just simply wanted to challenge myself (and not feel much regrets after).
Nevertheless, I don’t think it’s the norm to expect such outcomes in college. College isn’t high school.

Study enough to feel comfortable about the subject. That might mean 0 minutes a year (and not even bothering to attend class). Or that might mean all your free time.
And if you want to maintain a 3.0, aim for a 3.3. People tend to gain results lower than they expect.

You got all the time in the world during college. Some of my peers took 20+ credits a semester with a near full time job while maintaining a near 4.0 GPA.
Not saying you should expect a 3.5+ GPA but don’t think of it as being a trade off for “one less class per semester”.
The goal of attending college is to challenge yourself and hopefully “better yourself” within the 4 years. If your goal of college is to party and have fun instead of being a student, then college could end up being a poor investment vehicle for you.
Remember, once you leave to the real world, you are now competing against the market. A market which includes people from all over the world and a market in which some group of people are willing to work more than you for a lower pay. (e.g.: outsourcing)

Differential Equations is going to requite significantly more hours than any of the others: Calc I, II, Discrete math.
It also depends on your computational ability.
For Calc I, II, Discrete Math, I would assume like a few hour a week for most schools? Could be good enough to even justify an A.
For Differential Equations, I would assume whatever number of hours you spend in Calc II times 2.5~3 a week? Could be good to even justify an A.
It really depends how fast you grasp the concepts. If you could grasp the notion of Integration within a few minutes, then you probably understood the entirety of Calculus I and Calculus II right there. If not, oh well.

Internships trump GPA in the work force.
Especially once GPA is around 3.3.
Now, getting your first internship with a low GPA is a difficult one. How would companies judge whether to take a risk or not outside the GPA metric in the start?