Senior Year AP courses

If I want to get into Yale/ Harvard as a Political science major, what AP’s should I take my senior year in high school?

AP courses won’t get you in (or keep you out). You should have a balanced schedule comprised of all core subjects (math, science, English, history/social sciences, and foreign language) with several at the advanced level (which does not necessarily mean AP).

That said, AP US Gov/Comp Gov/Econ would probably be more useful than AP Physics C. Most applicants will have had calculus.

It should go without saying that HY will reject 95% of applicants, so make sure you have some affordable match/safety schools on your list.