<p>Dear Sir or Madam:</p>
<p>I am Chinese people and I am patients relative. The patient has contracted epilepsy for about 25 years. We seek medical help in all directions, but have not cured the sickness. Too bad is the patient finds out has contracted amyotrophic lateral sclerosis (ALS). Because the patient accepts a lot of treatments, for instance has buried the medicine on two arms, as well as has undergone the Nowlis Knife surgery. Whether contracts at present ALS and these treatments related? if related please provide the recovery plan which some should get sick, if has nothing to do with it please provide the sickness treatment plan, the medical information, the expert information and so on. If you suspect the diagnosis of ALS or others, also give your precious comment and the suggestion! Thanks!</p>
<p>Contact method:</p>
<pre><code>E_mail: zhzhch116@163.com
zhzhch116@tom.com
QQ: 175580937
</code></pre>
<p>We will appreciate any of your help. Thanks!</p>
<p>ZHANG Cheng</p>
<p>The patient material is as follows:</p>
<p>Patient Medical Record</p>
<p>Patient, male, 45 years old, a farmer</p>
<p>Disease with: Amyotrophic Lateral Sclerosis (namely a kind of Motor Neuron Disease) and Epilepsy</p>
<p>Thereinto: The patient is diagnosed contracts ALS in his March, and this sickness has more than two years; Epilepsy has 25 years approximately.</p>
<p>The patient present situation</p>
<li>Amyotrophic Lateral Sclerosis (ALS)</li>
</ol>
<p>1) His left hand finger can not extend at present. His right hand finger can extend except for the pink finger. </p>
<p>2) His both hands strength is very small, and his both hands also take the thing to tremble. Thereinto, his right hand strength is slightly bigger than his left hand. His left hand extends slightly high compared to his right hand, also his right hand extends high that would be stabbing pain forcefully.</p>
<p>3) His two arm muscles twitching, in which his left arm muscle twitching is more serious than his right arm.</p>
<p>4) His double lower limb not obvious characteristic, only is walks slowly, sometimes his knee stabbing pain, his leg muscle also occasionally twitching.</p>
<p>5) His buttocks muscle twitching slightly fiercely, his waist also sometimes aches, his anus occasionally stabbing pain.</p>
<p>6) Behind his neck has one hollowly, also the neck also feels not comfortably. His back and scalp have the contraction feelings.</p>
<p>7) Treats ALS medicine: Creatine Capsule, Cobamamide Tablets, Vitamin B1</p>
<li>Epilepsy</li>
</ol>
<p>1) The epileptic seizure aura: His brains feeling is uncomfortable (how uncomfortable patient can’t say specifically).</p>
<p>2) Status epileptics: When the patient disease seizure, his body would be backward falls, the mouth spits the foam, the mandibular joint shuts tightly, twitches, shows the whites of the eyes, the fierce time hands and feet also moves heedlessly also in the mouth feeds back the blood.</p>
<p>3) The epileptic seizure frequency: The disease seizure frequency approximately every 40 days one time to every 10 days one time, approximately average every 20 days one time. During the disease seizure period, the disease seizure would be continuously many times. The disease seizure duration time would be about 2~3 minutes to 5~6 minutes.</p>
<p>4) After epileptic seizure: The brains are not sober, and a slight ache. His hand moves heedlessly. </p>
<p>5) Treats epilepsy medicine: sodium valproate tablets, Carbamazepine</p>
<p>Case History</p>
<p>1) In 1964，the patient contracts encephalitis, when he was 1 year old.</p>
<p>2) In 1980, the patient began to disease seizure and finds out epilepsy.</p>
<p>3) In 1991, the patient began to accept epilepsy treatment in Zibo Jianguo hospital. </p>
<p>4) In 1993, the patient began to perform the surgery to treat through buries the medicine on two arms in Shandong Province Sishui County Tuberculosis Hospital.</p>
<p>5) In 2002, the patient began to perform the Nowlis Knife surgery to treat in Zibo Wanjie hospitals.</p>
<p>6) In 2004, the patient began to accept treatment in Beijing Daxing epilepsy special hospital. </p>
<p>7) In January, 2007, the patient began to accept treatment in Zibo Red Cross Changguo Hospital. </p>
<p>8) In March, 2007, the patient began to be diagnosed with ALS in Beijing Big Hospital, and accept its ALS and epilepsy treatment.</p>
<p>Particular Case History</p>
<p>1) In 1964，the patient contracts encephalitis, when he was 1 year old. The patient’s symptom is that he had a fever and showed the whites of the eyes at that time.</p>
<p>2) In 1980, the patient began to disease seizure and finds out contract the epilepsy in local hospital through the electroencephalogram.</p>
<p>Treats epilepsy medicine: Phenytoin Sodium, Vitamin B1, Nitrazepam Tablets</p>
<p>3) In July, 1991, the patient began to accept epilepsy treatment in Zibo Jianguo hospital.</p>
<p>Disease situation:</p>
<pre><code>Seizure aura: The chest is stuffy
Symptom: The mouth spits the foam, and the four limbs spasm.
Eye: Turns stares
Mouth: the tooth fastens nips
After alleviation: Wants to sleep, the asthenia, the headache
Ordinary behavior: Normal
</code></pre>
<p>Treatment medicine: Phenytoin Sodium, Nitrazepam Tablets. Moreover, Chinese medicine prescription invalid.</p>
<p>Inspection situation:</p>
<pre><code>Intelligence: Normal
Appetite: Normal
Physique: Good
Electroencephalogram: Normal
Electrocardiogram: Normal
</code></pre>
<p>Processing: Takes the period response to be good, after middle stops using 25 day to start to manifest suddenly</p>
<p>Effect: The effect of takes medicine period would be good. The patient began to seizure after stopping medicine 25 days.</p>
<p>4) In 1993, the patient began to perform the surgery to treat through buries the medicine on two arms in Shandong Province Sishui County Tuberculosis Hospital.</p>
<p>The patient had five times surgery treatment through buries the medicine on two arms. This surgery average every 40 days one time, in which left arm three times, and right arm two times.</p>
<p>Treatment medicine: Carbamazepine, Phenytoin Sodium, Oryzanol, Vitamin C, Calcium Saccharide Tablets, A.T.P, V.B.6, Nitrazepam Tablets, Phenobarbital Tablets</p>
<p>The patient did not allow eating the fat, the lard, the mutton, the smoke, and the alcohol. The patient may eat thin pork, the chicken, the fish, the duck and the animal internal organs and so on. And the patient should not eat some irritant foods including pungently, and not drink the tea.</p>
<p>During the two years from beginning to perform the surgery, the patient had seizure aura, but not seizure! Then, according to the hospital stipulation, he began to reduce the dose and seizure.</p>
<p>5) In 2002, the patient began to perform the Nowlis Knife surgery to treat in Zibo Wanjie hospitals.</p>
<p>The patient performed the Nowlis Knife surgery. And at the same time, he also takes the epilepsy medicine which the hospital compound.</p>
<p>6) In 2004, the patient began to accept treatment in Beijing Daxing epilepsy special hospital. </p>
<p>Treatment medicine: Carbamazepine, Magnesium Valproate Tablets, ZhiXianLing</p>
<p>In the first two years, the patient status was very well. Then, the patient restores slowly to beforehand condition. Therefore, the doctor removes Magnesium Valproate Tablets, changes eats Valpromide.</p>
<p>7) In January, 2007, the patient began to accept treatment in Zibo Red Cross Changguo Hospital.</p>
<p>Treatment medicine:QuTanZhenJing Capsule, Compound Phenobarbital Nitrazepamand Chlorphenamine Maleate Tablets, XiFengZhenJingYiKangDai</p>
<p>8) In March, 2007, the patient began to be diagnosed with ALS in Beijing Big Hospital, and accept its ALS and epilepsy treatment.</p>
<p>In Beijing, after experts consultation, they determined that the patient contracts ALS. Henceforth, he began to accept the hospital treatment.</p>
<p>① Treats ALS medicine: Creatine Capsule, Cobamamide Talbets, Vitamin B1.</p>
<p>② Treats epilepsy medicine: sodium valproate tablets, Carbamazepine</p>
<p>9) The patient other ALS situations</p>
<p>In 1999, the patient left hand thumb was bitten by the pig, and then was injected sterilization liquid. Then, his index finger could not extend. The patient could not to talk clearly when this symptom began.</p>
<p>At the beginning of 2005, the patient left hand finger cannot extend, and the hand strength has been small. His right hand is normal</p>