In general you want to take four years of Math, English, Science, Social Studies, and Foreign Language as well as any other courses needed to graduate HS. Colleges are not looking for students to specialize in HS. Of course, electives can be of your choosing.
If you are looking towards competitive colleges, take the most rigorous courseload you can comfortably manage. Work with your teachers and guidance counselor to create a program that makes sense for you.