Will colleges care if I take trigonometry regular over honors?

After this I am taking AP calc AB, then either AP stats or multi variable calc. Besides math, I am taking the hardest courses availabe to me. Will this reduce my chances of getting into UC’s?

I can’t imagine they will care TOO much since you are planning on taking an AP math course after. If you can handle and fit the honors version into your schedule, it would be looked upon more favorably.