You’ll need to see admissions requirements. For example, University of Maryland Baltimore counts all grades in GPA, including classes taken more than once, and also calculates a Science GPA.
Many schools use centralized website for the PA application
“ All repeated course grades are counted in the CASPA GPA calculation. For information on how CASPA calculates GPAs, please go to their Frequently Asked Questions Web page at https://portal.caspaonline.org/caspaHelpPages/frequently-asked-questions/. ”
Also need” Applicants must also complete three (3) Letters of Recommendation, a Personal Statement and Patient Contact Experience history (a minimum of 1400 hours is preferred) in the CASPA application.”
Patient Contact Experience must be a paid position. You may need a four month certification class to become EMT, for example. https://graduate.umaryland.edu/media/Graduate-School/Documents/PA-Admissions-Booklet.pdf