D-Mannose?

<p>Has anyone had success with using this supplement to prevent or treat urinary tract infections? I got some yesterday and have started taking it twice a day.</p>

<p>I’m going to try to revive this in case anyone has experience with this supplement. I’m running out of treatment options.</p>

<p>bethie - stay tuned, I’m digging through Pubmed. I got curious since I never heard of that one. I suspect that a small amount of mannose will not hurt you.</p>

<p>D-mannose is a common enough sugar. I’ve never heard of being used as medicine for anything. It looks like BB is already perusing the literature. Let’s see what she finds.</p>

<p>Nothing works for me. I have to take a prophylactic antibiotic (nitrofurantoin) daily, or I get a UTI. I haven’t tried D-Mannose, but just about everything else (well, except celibacy which DH would not be too happy about).</p>

<p>My urologist said that they actually implanted bacteria in 100 women. The women then drank a lot of water. In 98 of the women, the bacteria flushed out. The other two women both got UTIs. I guess I’m in the lucky 2% whose body won’t flush out the bacteria (I drink a lot of water!).</p>

<p>MaineLonghorn–my urologist told me about that (horrid, imo) study too. So what if some women can naturally fight off the infection?! Some of us can’t. I’ve been having frequent UTIs since I was 17 and I’m now 60. I’ll try anything. The antibiotics don’t work forever.</p>

<p>Maybe those 2 women were in a higher risk category:</p>

<p>[Urinary</a> tract infection (UTI): Risk factors - MayoClinic.com](<a href=“Urinary tract infection (UTI) - Symptoms and causes - Mayo Clinic”>Urinary tract infection (UTI) - Symptoms and causes - Mayo Clinic)</p>

<p>Still digging through literature; it is a slow process on a smartphone, and there is a lot of pseudo-science on the web, as it is always the case with supplements. :slight_smile: I’m not concerned about mannose - as coureur said, it is a natural carbohydrate.</p>

<p>Here is a good popular science read:</p>

<p>[Is</a> D-mannose Better Than Cranberry For Uti? | LIVESTRONG.COM](<a href=“http://www.livestrong.com/article/486458-is-d-mannose-better-than-cranberry-for-uti/]Is”>Is D-mannose Better Than Cranberry for UTI? | Healthfully)</p>

<p>There are some abstracts in Pubmed that suggest that mannose and its derivatives prevent some types of bacteria from adhering to urinary tract:</p>

<p>[Antiadhesion</a> therapy for urinary tract - PubMed Mobile](<a href=“Antiadhesion therapy for urinary tract infections--a balanced PK/PD profile proved to be key for success - PubMed”>Antiadhesion therapy for urinary tract infections--a balanced PK/PD profile proved to be key for success - PubMed)</p>

<p>[url=&lt;a href=“Natural approaches to prevention and treatment of infections of the lower urinary tract - PubMed”&gt;Natural approaches to prevention and treatment of infections of the lower urinary tract - PubMed]Natural</a> approaches to prevention and tr - PubMed Mobile<a href=“not%20sure%20about%20this%20one”>/url</a></p>

<p>Thanks, BB! It sounds like a safe thing to try, until more is known. As to antibiotics, if Cipro stops working for me, I don’t know what to do next.</p>

<p>Bethievt, what is your diagnosis? Many women are prone to UTI’s, especially those with diabetes. Do you have any scarring of the bladder, stones or difficulty with retention? Some women find relieve of frequent UTI’s that are not based on any specific pathology by: using unscented, white toilet tissue, wiping front to back, wearing cotton lined panties, and voiding immediately after intercourse. I found a female urologist for my mother, one who specialized in treatment options for women, it made a significant difference! Hope you feel better.</p>

<p>I’ve had at least 3 cystoscopies, one of them recent and there’s no visible problem. I don’t have diabetes, fortunately, and I follow all those types of suggestions you mention. My only diagnosis is recurrent UTIs.</p>

<p>My urologist is highly-respected and has been in practice a long time. His PA told me that the antibiotics might stop working at some point. I was concerned enough that I made a specific appointment with the doctor. He told me that none of his patients have developed a resistance to nitrofurantoin (Macrobid) and he sees no possibility of that with me. The other benefit of Macrobid is that it does not cause yeast infections. I, also, have had quite a few tests run and don’t have diabetes.</p>

<p>I will continue taking Macrobid since that’s what the doctor says will work. I have tried all the tips recommended in post #11 with no luck. (I still take cranberry supplements daily.) I can’t fool around with this - one of my UTI’s progressed to my kidneys in 1996 and I ended up in the hospital for five days. The pain was worse than childbirth.</p>

<p>But post an update as to how it goes with D-Mannose. I’m always willing to try something new.</p>

<p>I will keep you posted, MaineLonghorn. I’ve been on prophylactic Macrobid in the past, also a sulfa drug. Maybe it’s time to go back to Bactrim.</p>

<p>Do either of you have difficulty emptying your bladder completely?</p>

<p>You can also try probiotics with lactobacilli. Avoid using diaphragms diaphragms spermicide coated condoms.</p>

<p>ECmotherx2</p>

<p>Yes, some retention, but my urologist couldn’t see anything that could be fixed by surgery. He’s a surgeon, so I think he would have said. Birth control is many years in my past.</p>

<p>No, no trouble emptying. I don’t have to go very often, though. I’m trying to make myself go more often than when I feel the urge. No more BC here, either.</p>

<p>Yes, distention can be as much a problem as retention.</p>

<p>I would try the probiotics with lactobacilli. If retention becomes an issue, this can lead to UTI’s, there is a medication that acts on the smooth muscle of the bladder and will assist in contraction and proper emptying.</p>