So this trimester, I got A in one of my honors classes, a A in Algebra 2 A, A in college readiness, C- in Honors Chemistry, and a C in AP US History 
I really want to go to University of Michigan…Is it end of the world? Plz help meh
No. Nothing is ever “end of the world” 
Relax! I’m assuming you aren’t a senior in high school. In that case, just try to get better scores in those subjects in the future. As long as you have an upward trend in your grades a couple of Cs will not kill you. Try to find out why you didn’t get the scores you wanted in those subjects and fix them for the future. Keep at it! Good Luck!
depends on your major
I am actually a Sophomore, done with 2nd trimester
And my GPA so far is 3.5 not including this trimester grades…
And my major is somewhere in medical science